BRM/BRG1 ATP-IN-7

SKU: orb3173648

Description

BRM/BRG1 ATP-IN-7 (Compound Cpd69) functions as a selective dual inhibitor, effectively targeting BRM (SMARCA2) and BRG1 (SMARCA4) with IC50 values of 12 nM and 8 nM, respectively. It shows potential for research in BRM/BRG1-dependent cancers, such as non-small cell lung cancer and Ewing's sarcoma, as well as virus-associated diseases like HPV infection.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2468048-19-1
• MW: 511.57
• Formula: C₂₃H₂₁N₅O₅S₂
• SMILES: N(C([C@@H](NC(=O)C1=CN(S(C)(=O)=O)C=C1)CO)=O)C2=NC(=CS2)C3=CC(=CC=C3)C=4C=CN=CC4
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Epigenetic Reader Domain