BRK/PTK6-IN-1

SKU: orb3173473

Description

BRK/PTK6-IN-1 (Compound 51) is a potent and selective BRK inhibitor with an IC50 of 3.37 nM and Kd of 44 nM. It reduces MMP-9 protein expression and inhibits IGF-1-induced AKT phosphorylation in MDA-MB-231 cells. This compound significantly hinders migration, invasion, and colony formation without affecting cell proliferation and is commonly used in breast cancer and other cancer research.

Key Properties

• Target: BTK,Akt,MMP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

BTK,Akt,MMP