Brimarafenib

SKU: orb2664420

Description

Brimarafenib is a selective RAF dimerization inhibitor that potently targets BRAF and CRAF, including various BRAF mutations and fusions. It is utilized in preclinical research for studying MAPK pathway-driven solid tumors, such as colorectal and pancreatic cancers, in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1643326-82-2
• MW: 482.41
• Purity: 98.32% (May vary between batches)
• Formula: C₂₄H₁₇F₃N₄O₄
• SMILES: N(C(NC1=C(F)C=C(F)C(F)=C1)=O)[C@H]2[C@]3([C@@]2(OC=4C3=CC(OC5=C6C(NC=C5)=NC(=O)CC6)=CC4)[H])[H]
• Target: Raf

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Brimarafenib, Brimarafenibum, BGB3245, BGB-3245, BGB 245, BGB245

Compound Identifiers

PubChem CID

117807031