Brevifolincarboxylic acid

SKU: orb1297440

Description

Brevifolincarboxylic acid, isolated from Polygonum capitatum, acts as an aryl hydrocarbon receptor (AhR) inhibitor and an α-glucosidase inhibitor (IC50 = 323.46 µM). This compound is a useful research tool for studying metabolic disorders and AhR-mediated pathways in biochemical and cellular assays.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 18490-95-4
• MW: 292.2
• Purity: 99.42% (May vary between batches)
• Formula: C₁₃H₈O₈
• SMILES: OC(=O)C1CC(=O)c2oc(=O)c3cc(O)c(O)c(O)c3c12
• Target: Glucosidase|||Aryl Hydrocarbon Receptor|||AhR
• Solubility: DMSO:50.00 mg/mL (171.12 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.50 mg/mL (1.71 mM)

Bioactivity

• Target IC50:
  α-glucosidase:323.46 μM (α-glucosidase) (IC50)
• In Vitro:
  The structure of these compounds was elucidated by 1H, 13C 1D NMR and mass spectrometry experiments. The antibacterial activity against Salmonella strains and antioxidant activity of the crude extract, fractions and isolated compounds was evaluated using the DPPH method. The isolated compounds identified as Brevifolincarboxylic acid and gallic acid demonstrates moderate antibacterial activity against Salmonella enteritidis , Salmonella typhimurium , and Salmonella abony
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

α-glucosidase, Brevifolincarboxylic acid, Aryl Hydrocarbon Receptor, ArylHydrocarbonReceptor, Antifection, AhR, ahr, inhibit, Inhibitor, Glucosidase

Compound Identifiers

PubChem CID

9838995