BRD5529

SKU: orb1707514

Description

BRD5529 is a selective small molecule inhibitor that disrupts the CARD9-TRIM62 protein-protein interaction (IC50 = 8.6 µM). It blocks TRIM62-mediated ubiquitination and subsequent activation of CARD9, serving as a useful tool for studying CARD9 signaling in innate immunity and inflammation research, both in vitro and in vivo.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1358488-78-4
• MW: 465.55
• Formula: C₂₅H₃₁N₅O₄
• SMILES: O=C(O)C1=CC(=CN=C1N2CCC(C(=O)N)(N3CCCCC3)CC2)NC(=O)C4=CC=C(C=C4)C
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

83288403