BRD4 Inhibitor-27

SKU: orb1944540

Description

BRD4 Inhibitor-27 is a potent, dual-bromodomain inhibitor targeting BRD4 BD1 and BD2 with IC50 values of 9.6 and 11.3 µM, respectively. It exhibits anticancer activity and is a useful chemical probe for breast cancer research in both cellular and animal models.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 930039-92-2
• MW: 346.31
• Purity: 99.92% (May vary between batches)
• Formula: C₁₆H₁₃F₃N₆
• SMILES: FC(F)(F)C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN12
• Target: Epigenetic Reader Domain
• Solubility: DMSO:55 mg/mL (158.82 mM)

Bioactivity

• Target IC50:
  BD2:11.3 uM|BD1:9.6 uM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EpigeneticReaderDomain, Epigenetic Reader Domain, BRD4-BD2, BRD4-BD1, BRD4 Inhibitor27

Compound Identifiers

PubChem CID

17395684