BRD4 Inhibitor-18

SKU: orb1686691

Description

BRD4 Inhibitor-18 is a potent small molecule (IC50 = 110 nM) featuring a hydrophobic acetylcyclopentane moiety. It effectively suppresses proliferation in BRD4-high leukemia cells like MV-4-11 by inducing cell cycle arrest in G0/G1 phase and promoting apoptosis, making it a valuable tool for epigenetic and cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2451219-73-9
• MW: 496.02
• Formula: C₂₆H₂₆ClN₃O₃S
• SMILES: CN1C=2C=3C(C(=NC(CC(NC4CCCC4)=O)C2SC1=O)C5=CC=C(Cl)C=C5)=CC(OC)=CC3
• Target: Others,c-Myc,Apoptosis,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156016820