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BRD4-IN-4

SKU: orb1819110

Description

BRD4-IN-4 is a selective BRD4 inhibitor (IC50 = 6.83 µM) that suppresses proliferation and induces G1 phase arrest in MV4-11 leukemia cells. It serves as a useful chemical probe for investigating BRD4 biology and studying mixed-lineage leukemia (MLL) in cellular research models.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number304685-40-3
MW330.4
Purity>99.99% (May vary between batches)
FormulaC17H18N2O3S
SMILESCCN1C(=O)C2=CC=CC3=C(C=CC1=C23)S(=O)(=O)N1CCCC1
TargetEpigenetic Reader Domain
SolubilityDMSO:45 mg/mL (136.2 mM)

Bioactivity

Target IC50
BRD4:6.83 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BRD4, BRD4IN4, BRD4-IN-4, EpigeneticReaderDomain, Epigenetic Reader Domain

Similar Products

  • BRD4-IN-4 [orb2900518]

    >98% (HPLC)

    304685-40-3

    330.4

    C17H18N2O3S

    1 g, 500 mg, 25 mg, 50 mg, 100 mg, 5 mg, 10 mg
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

BRD4-IN-4 (orb1819110)

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10 mg
$ 80.00
25 mg
$ 90.00
50 mg
$ 120.00
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