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BRD4 degrader-5

SKU: orb2944502

Description

BRD4 degrader-5 (Compound 23) is a hydrophobic-tagged molecule that induces BRD4 degradation via ER stress and autophagy, exhibiting a DC50 of 24.7 µM. It demonstrates anti-proliferative activity in 4T1 cancer cells with an IC50 of 20.6 µM, supporting its use in oncology research for studying targeted protein degradation.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW660.27
FormulaC35H42ClN7O2S
TargetEpigenetic Reader Domain,Autophagy,AUTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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BRD4 degrader-5 (orb2944502)

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