BRD4-BD1/2-IN-3

SKU: orb3134900

Description

BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-κB signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin

Key Properties

• CAS Number: 3106588-54-6
• MW: 362.39
• Purity: 99.63% (May vary between batches)
• Formula: C₂₀H₁₈N₄O₃
• SMILES: O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=NN(C3)CC=4C=CC=CC4
• Target: Others,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,Epigenetic Reader Domain