BRD4-BD1-IN-2

SKU: orb1685922

Description

BRD4-BD1-IN-2 is a potent and selective inhibitor of the BRD4 bromodomain 1 (BD1), exhibiting a 20-fold selectivity over BD2. This small molecule is a valuable chemical probe for investigating BRD4 function in cardiovascular and cancer research, applicable in both in vitro and in vivo experimental models.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin

Key Properties

• CAS Number: 2761321-26-8
• MW: 583.07
• Purity: 99.47% (May vary between batches)
• Formula: C₂₀H₁₅Br₃N₄O₂
• SMILES: C(N1C2=C(N=C1Br)N(C)C(=O)N(CC3=CC=C(Br)C=C3)C2=O)C4=CC=C(Br)C=C4
• Target: Epigenetic Reader Domain
• Solubility: DMSO:6.25 mg/mL (10.72 mM)

Bioactivity

• Target IC50:
  BRD4 BD2:50 μM|BRD4 BD1:2.51 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EpigeneticReaderDomain, Epigenetic Reader Domain, BRD4-BD1

Compound Identifiers

PubChem CID

155908591