BRD2492

SKU: orb1700964

Description

BRD2492 is a potent and selective dual inhibitor of HDAC1 and HDAC2, also active against HDAC3 and HDAC6. It demonstrates antiproliferative and pro-apoptotic activity in breast cancer cell lines in vitro, supporting its investigation as a potential anticancer agent.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1821669-43-5
• MW: 346.38
• Purity: 99.56%
• Formula: C₂₀H₁₈N₄O₂
• SMILES: O=C(NC=1C=C(C=CC1N)C=2C=CN=CC2)C3=CC=C(C=C3)NC(=O)C
• Target: HDAC

Bioactivity

• Target IC50:
  HDAC1:13.2 nM|HDAC3:8908 nM|HDAC6:>1000 nM|HDAC2:77.2 nM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HDAC, BRD2492, BRD-2492, BRD 2492

Compound Identifiers

PubChem CID

118987449