BRD0539

SKU: orb1704844

Description

BRD0539 is a cell-permeable small molecule inhibitor of Streptococcus pyogenes Cas9 (SpCas9). It functions by preventing the binding of SpCas9 to DNA, thereby blocking its nuclease activity. This inhibitor is a valuable research tool for controlling CRISPR-Cas9 genome editing in both cellular and animal models.

Research Area

Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 1403838-79-8
• MW: 452.54
• Purity: 98.03% (May vary between batches)
• Formula: C₂₅H₂₅FN₂O₃S
• SMILES: [H][C@]12CCN([C@@]1([H])c1cc(ccc1N[C@H]2CO)-c1ccccc1F)S(=O)(=O)c1ccc(C)cc1
• Target: CRISPR/Cas9

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54666326