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BRCA2-RAD51-IN-3

SKU: orb3210088

Description

BRCA2-RAD51-IN-3 is an inhibitor of the RAD51-BRCA2 protein interaction, exhibiting an EC50 of 29.35 μM and a Kd of 75.14 μM. It disrupts the binding of RAD51 to BRCA2, impairing homologous recombination in cancer cells and inducing synthetic lethality. BRCA2-RAD51-IN-3 is effective against human pancreatic cancer cells, with no activity in normal pancreatic cells, and is applicable in pancreatic cancer research.

Images & Validation

Key Properties

TargetDNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information