Brassinazole

SKU: orb1689105

Description

Brassinazole is a triazole-type selective inhibitor of brassinosteroid biosynthesis. It is widely used in plant physiology research to modulate BR signaling, enabling the study of xylem development and other growth processes in both in vivo and in vitro experimental systems.

Research Area

Metabolism Research

Key Properties

• CAS Number: 280129-83-1
• MW: 327.81
• Purity: 99.71% (May vary between batches)
• Formula: C₁₈H₁₈ClN₃O
• SMILES: [C@H]([C@@](C)(O)C1=CC=CC=C1)(CC2=CC=C(Cl)C=C2)N3C=NC=N3
• Target: Cytochromes P450,Others
• Solubility: DMSO:30 mg/mL (91.52 mM)

Bioactivity

• In Vitro:
  At concentrations of 0.5, 1, and 5 μM, Brassinazole induces marked malformation of seedlings, rendering them morphologically similar to BR-deficient mutants. Cress treated with Brassinazole exhibits dwarfism and altered leaf morphology, characterized by downward curling and a dark green color typical of Arabidopsis BR-deficient mutants. This dwarfism is reversed by the application of 10 nM brassinolide .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

brassinosteroid biosynthesis, (2S,3R)-Brassinazole

Compound Identifiers

PubChem CID

92846666