Brain Derived Basic Fibroblast Growth Factor (1-24)

SKU: orb3053953

Description

Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research.

Key Properties

• CAS Number: 211362-85-5
• MW: 2553.86
• Purity: >98% (HPLC)
• Formula: C₁₁₈H₁₇₃N₃₁O₃₃
• Solubility: DMSO : 100 mg/mL (39.16 mM; ultraphonic; )

Bioactivity

• In Vitro:
  Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 12 h) inhibits the growth of Streptococcus pneumoniae. Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 6 d) inhibits HBV replication of HepG2-2.2.15 cells. Brain Derived Basic Fibroblast Growth Factor (1-24) (10 μg/mL; 22 h) inhibits the migration of human endothelial cell. Cell Viability Assay Cell line: Streptococcus pneumoniae. Concentration: 10 μg/mL. Incubation time: 12 hours. Result: Inhibited by 100% the growth of Streptococcus pneumoniae. RT-PCR Cell line: HepG2-2.2.15 cells Concentration: 10 μg/mL. Incubation time: 6 days. Result: Inhibited by 31.4% HBV replication as compared to the virus control infection. Cell Migration Assay Cell line: Human endothelial cells (HUVEC). Concentration: 10 μg/mL. Incubation time: 22 hours. Result: Inhibited by 17% the migration of human endothelial cells

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only