Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Braftide

SKU: orb2563646

Description

Braftide is an allosteric BRAF kinase inhibitor that disrupts dimer formation, targeting both wild-type and oncogenic variants like BRAFG469A. It suppresses MAPK signaling and inhibits proliferation in KRAS-mutant colorectal cancer cell lines such as HCT116 and HCT-15, making it a tool for studying oncogenic BRAF signaling in vitro.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetRaf,Ras,Kras
CAS Number2411851-64-2
MW1243.52
FormulaC57H94N16O13S
SMILES[C@@H](CC1=CN=CN1)(NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCSC)C(O)=O)=O)=O)CC(C)C)=O)CC(C)C)=O)[C@H](CC)C)=O)CC(N)=O)=O)[C@H](C)C)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Tat-braftide [orb1479253]

    > 95% by hplc

    2990.47 Da

    H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Gln-PEG-Thr-Arg-His-Val-Asn-Ile-Leu-Leu-Phe-Met-OH

    1 mg
  • Tat-braftide [orb3142362]

    50 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide