BRAF V600E/CRAF-IN-1

SKU: orb1686595

Description

BRAF V600E/CRAF-IN-1 is a potent, selective inhibitor of BRAF V600E and CRAF kinases. It induces G0/G1 phase cell cycle arrest and apoptosis in HCT-116 colon cancer cells in vitro, showing potential for oncology research in both cellular and animal models of RAF-driven cancers.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2499499-56-6
MW	505.41
Formula	C₂₅H₁₇F₆N₃O₂
SMILES	O(C)C=1C2=C(N=C(NC3=CC(NC(=O)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=CC=C3)C=C2)C=CC1
Target	Raf,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

162664089 ↗

Key Properties

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No computed properties available.

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