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BR351 precursor

SKU: orb1710213

Description

BR351 precursor is metabolized to BR351, a brain-penetrant matrix metalloproteinase inhibitor. It potently inhibits MMP2, MMP8, MMP9, and MMP13 with IC50 values in the low nanomolar range. This compound is a valuable research tool for studying MMP roles in neurological disorders, cancer metastasis, and inflammatory processes in both cellular and animal models.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number960113-89-7
MW576.68
FormulaC27H32N2O8S2
SMILESN([C@@H](C(NO)=O)[C@@H](C)C)(S(=O)(=O)C1=CC=C(OCCOS(=O)(=O)C2=CC=C(C)C=C2)C=C1)CC3=CC=CC=C3
TargetMMP,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information