BQZ-485

SKU: orb2277709

Description

BQZ-485 is a potent and selective GDI2 inhibitor that disrupts the GDI2-Rab1A interaction by targeting Tyr245. This inhibition blocks ER-to-Golgi vesicular transport, inducing paraptosis, and serves as a valuable chemical probe for studying intracellular trafficking and cell death mechanisms in cancer research.

Research Area

Cell Biology

Key Properties

• CAS Number: 1906915-49-8
• MW: 485.66
• Formula: C₃₂H₃₉NO₃
• SMILES: O(CC1=CC(C)=CC(C)=C1)C=2C=C3[C@@]4(N(CCC3=CC2OCC5=CC(C)=CC(C)=C5)[C@@H](C)C[C@H](O)C4)[H]
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169450671