BPTES

SKU: orb1222374

Description

BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex.

Key Properties

• CAS Number: 314045-39-1
• MW: 524.68
• Purity: >98% (HPLC)
• Formula: C₂₄H₂₄N₆O₂S₃
• SMILES: O=C(Cc1ccccc1)Nc1nnc(s1)CCSCCc1sc(nn1)NC(=O)Cc1ccccc1
• Target: Sirtuin
• Solubility: DMSO : 50 mg/mL 95.30 mM;H2O : < 0.1 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BPTES

Quick Database Links

Gene Symbol

Sirtuin