BPR1K871

SKU: orb1710220

Description

BPR1K871 is a preclinical dual inhibitor targeting FLT3 and AURKA kinases with IC50 values of 19 nM and 22 nM, respectively. It is utilized in cancer research for investigating acute myeloid leukemia (AML), demonstrating anti-proliferative effects in cellular assays and reducing tumor burden in xenograft models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2443767-35-7
• MW: 526.05
• Formula: C₂₅H₂₈ClN₇O₂S
• SMILES: CN(C)CCCOc1ccc2c(NCCc3cnc(NC(=O)Nc4cccc(Cl)c4)s3)ncnc2c1
• Target: FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

126970666