BPIQ-II (hydrochloride)

SKU: orb1693445

Description

BPIQ-II is a potent and highly selective linear imidazoloquinazoline inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 8 pM). It acts as a competitive ATP-site binder, effectively blocking EGF-stimulated signaling in cellular assays, making it a valuable tool for cancer research and studying EGFR-driven pathways in vitro.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 171179-37-6
• MW: 376.64
• Formula: C₁₅H₁₁BrClN₅
• SMILES: Cl.BrC1=CC=CC(=C1)NC2=NC=NC3=CC=4N=CNC4C=C32
• Target: Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132988087