BPDA2

SKU: orb1744075

Description

BPDA2 is a potent and selective SHP2 inhibitor (IC50 = 92.0 nM) with demonstrated anticancer activity. It suppresses breast cancer cell proliferation, anchorage-independent growth, and cancer stem cell properties in vitro, making it a valuable tool for oncology and signaling pathway research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2907659-86-1
• MW: 398.49
• Purity: 99.80% (May vary between batches)
• Formula: C₂₄H₃₀O₅
• SMILES: O=C(O)C=1C=C(C=CC1OCCCCCCCCC)C2=CC=C(C=C2)CC(=O)O
• Target: Phosphatase

Bioactivity

• In Vitro:
  In JIMT-1 and MDA-MB468 cells, BPDA2 (0.2, 0.4, 0.8, 1.6, 3.2 μM) inhibited basal activation of Akt and ERK1/2 in a concentration-dependent manner.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SHP-2

Compound Identifiers

PubChem CID

166642571