Bosentan-d4

SKU: orb1983432

Description

Bosentan-d4 is a deuterated isotopologue of the dual endothelin receptor antagonist Bosentan. It competitively inhibits both ETA (Ki=4.7 nM) and ETB (Ki=95 nM) receptors, making it a valuable internal standard for quantifying Bosentan in pharmacokinetic studies and for probing endothelin system function in cardiovascular research models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1065472-77-6
• MW: 555.64
• Formula: C₂₇H₂₅D₄N₅O₆S
• SMILES: [2H]C([2H])(O)C([2H])([2H])Oc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1
• Target: Endothelin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25217741