Boc-NH-PEG4-CH2COOH

SKU: orb1217547

Description

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

Images & Validation

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Key Properties

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CAS Number	876345-13-0
MW	351.39
Purity	>98% (HPLC)
Formula	C₁₅H₂₉NO₈
SMILES	O=C(O)COCCOCCOCCOCCNC(OC(C)(C)C)=O
Target	ADCs Linker/Click Chemistry

Bioactivity

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In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

ADCs Linker/Click Chemistry

Protocol Information

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