Boc-C14-COOH

SKU: orb1297882

Description

Boc-C14-COOH is a 14-carbon alkyl chain linker featuring a terminal carboxylic acid for conjugation. It serves as a non-cleavable linker in ADC development and as a spacer in PROTAC design for targeted protein degradation, applicable in both in vitro and in vivo cancer research.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 843666-27-3
• MW: 342.513
• Purity: ≥98% (May vary between batches)
• Formula: C₂₀H₃₈O₄
• SMILES: O=C(O)CCCCCCCCCCCCCCC(OC(C)(C)C)=O
• Target: ADC Linker,PROTAC Linker

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibody-drug conjugates linkers, BocC14COOH, Boc-C-14-COOH, Boc-C14-COOH, Boc C14 COOH, ADCLinker, ADC Linkers, ADC Linker, Alkyl-Chain, inhibit, Non-cleavable, Inhibitor, PROTACLinker, PROTAC Linker, PROTAC Linkers

Compound Identifiers

PubChem CID

57817723