BMS-986339

• Catalog Number: orb1744391
• Category: Small Molecules
• Description: BMS-986339 is an orally active, potent FXR agonist that engages His298 and ASN287 residues via H-bond formation. It is employed in research on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) due to its anti-fibrosis properties.
• Purity: 98.00%
• MW: 643.71
• Biological Activity: BMS-986339 is an orally active, potent FXR agonist that interacts via H-bond formation with the His298 and ASN287 residues. It is utilized in research focused on primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and nonalcoholic steatohepatitis (NASH) for its anti-fibrosis properties.
• CAS Number: 2477873-64-4
• Formula: C₃₅H₄₁F₄N₃O₄
• SMILES: C(C)(C)(F)C1=NC(C23CCC(CN(C(=O)[C@H]4C[C@@](C(F)(F)F)(O)C4)C5=CC(=CC=C5)C6=CC=C(C(C)(C)O)C=C6)(CC2)CC3)=NO1
• Storage: -20°C
• Note: For research use only