BMS-986143

SKU: orb1691547

Description

BMS-986143 is a potent, reversible, and orally bioavailable BTK inhibitor (IC50=0.26 nM) developed for autoimmune disease research. It also potently inhibits related kinases like TEC, BLK, and ITK. This profile supports its use in both in vitro biochemical assays and in vivo models of B-cell mediated inflammatory conditions.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1643372-95-5
• MW: 587.45
• Formula: C₃₁H₂₄Cl₂N₄O₄
• SMILES: ClC=1C(=C2C(=C(C(N)=O)C1)NC=3C2=CC=C(C(C)(C)O)C3)C4=C(C)C(=CC=C4)N5C(=O)N6C(=CC5=O)C(Cl)=CC=C6
• Target: Others,BTK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86580694