BMS-737

SKU: orb2564442

Description

BMS-737 (compound 33) is a selective, reversible small-molecule inhibitor of CYP17 lyase with 11-fold selectivity over hydroxylase. It is designed for CRPC research, effectively suppressing testosterone in preclinical models while sparing upstream adrenal steroidogenesis, making it a tool for studying advanced prostate cancer mechanisms.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1356053-63-8
• MW: 306.30
• Formula: C₁₆H₁₁FN₆
• SMILES: FC1=CC=C(C=C1)N2N=CC=3C2=NC=CC3C=4C=NC=NC4N
• Target: Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56603071