BMS-554417

SKU: orb1740259

Description

BMS-554417 is a novel, orally bioavailable small molecule inhibitor targeting both IGF-IR and insulin receptor kinase activity. It inhibits cell proliferation in vitro, induces cell cycle arrest or apoptosis, and demonstrates significant anti-tumor efficacy in xenograft models by blocking downstream PI3K/Akt and ERK signaling pathways. This makes it a valuable research tool for studying IGF/insulin signaling in oncology and metabolic disease research.

Key Properties

• CAS Number: 468741-42-6
• MW: 532.04
• Formula: C₂₈H₃₀ClN₇O₂
• SMILES: N(C[C@@H](O)C1=CC(Cl)=CC=C1)C2=C(C=3NC=4C(N3)=CC(=CC4C)N5CCN(CCC#N)CC5)C(=O)NC=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135423375