BMS-502

SKU: orb1980151

Description

BMS-502 is a potent dual inhibitor of DGKα and DGKζ, enhancing T cell immune responses and blocking intracellular checkpoint signaling in a dose-dependent manner. It is a valuable research tool for studying immune-related diseases in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 2407854-18-4
• MW: 516.5
• Purity: 99.78% (May vary between batches)
• Formula: C₂₇H₂₂F₂N₆O₃
• SMILES: N#CC1=NC2=C(N(C)C(C([N+]([O-])=O)=C2N3CCN(C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3)=O)C=C1
• Target: Others
• Solubility: DMSO:80 mg/mL (154.89 mM)

Bioactivity

• Target IC50:
  DGKζ:2.1nM|DGKα:4.6 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BMS502, DGK

Compound Identifiers

PubChem CID

146466271