BMS-309403 sodium

SKU: orb1818889

Description

BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells.

Key Properties

• CAS Number: 2802523-05-1
• MW: 498.5474588871
• Purity: >98%
• Formula: C₃₁H₂₇N₂NAO₃
• SMILES: C(C1N(C2C=CC=CC=2C2C=CC=C(OCC(=O)O)C=2)N=C(C2C=CC=CC=2)C=1C1C=CC=CC=1)C.[NaH]

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only