BMS-214662 hydrochloride

SKU: orb1741254

Description

BMS-214662 is a nonsedating benzodiazepine-derived farnesyltransferase inhibitor with antineoplastic potential. It blocks protein farnesylation, disrupting Ras-mediated signaling to induce apoptosis in tumor cells, including those with and without Ras mutations, as demonstrated in both in vitro and in vivo cancer models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 195981-08-9
• MW: 526.07
• Formula: C₂₅H₂₄ClN₅O₂S₂
• SMILES: Cl.O=S(=O)(N1Cc2cc(ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1)C#N)c1cccs1
• Target: Ras,Others,Transferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44189294