BMS-214662 HCl

• Catalog Number: orb1741254
• Category: Small Molecules
• Description: BMS-214662 HCl
• CAS Number: 195981-08-9
• Purity: 0.98
• MW: 526.07
• SMILES: Cl.O=S(=O)(N1Cc2cc(ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1)C#N)c1cccs1
• Formula: C₂₅H₂₄ClN₅O₂S₂
• Biological Activity: BMS-214662 is a Farnesyltransferase inhibitor , is also a nonsedating benzodiazepine derivative with potential antineoplastic activity. BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. This agent may reverse the malignant phenotype of H-Ras-transformed cells and has been shown to be active against tumor cells with and without Ras mutations.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.