BMPR2-IN-1

SKU: orb2278115

Description

BMPR2-IN-1 (Compound 8a) is a potent and selective BMPR2 inhibitor with a Kd of 83.5 nM. This small molecule is a valuable research tool for investigating the role of BMPR2 signaling in diseases such as pulmonary arterial hypertension, Alzheimer's disease, and cancer, in both cellular and animal models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• MW: 321.34
• Formula: C₁₆H₁₅N₇O
• SMILES: O=C1C2=CC(NC3=CC=NC(NC4=CC=C(CCN1)C=C4)=N3)=NN2
• Target: TGF-beta/Smad,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168475951