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Description

BMP-4 is a heparin-binding peptide with demonstrated anti-inflammatory and anti-chondrogenic activity. In vitro and in vivo studies show it suppresses key inflammatory mediators like iNOS, COX-2, and IL-6 via the iNOS-IFN-IL6 pathway, mitigating arthritis symptoms in murine models.

Research Area

Immunology & Inflammation, Neuroscience, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetCOX,Interleukin,IFNAR
CAS Number1629625-47-3
MW1308.52
FormulaC52H93N25O13S
SMILESC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CS)=O)CC(N)=O)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCC2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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BMP-4 (orb2802026)

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