BLINK11

SKU: orb3028104

Description

BLINK11 is a blood-brain barrier-permeable inhibitor of Cdk5. It reduces the activity of CDK5 by targeting CDK5/p35 (IC50 = 17.09 nM) and CDK5/p25 (IC50 = 14.69 nM) complexes. BLINK11 exhibits antidiabetic and neuroprotective properties, lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive function, and reduces neurodegenerative lesions.

Research Area

Cell Biology

Key Properties

• CAS Number: 712339-45-2
• MW: 534.82
• Formula: C₂₅H₂₂Cl₃N₃O₄
• SMILES: O=C(NC1=C(Cl)C(Cl)=CC=C1)C2=CC=CC=C2OCC(NC3=CC(Cl)=C(N4CCOCC4)C=C3)=O
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK