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BKT-300

SKU: orb3027399

Description

BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1), with a Kd value of 28.3 nM. It disrupts microtubule architecture, induces G2/M phase arrest, mitotic catastrophe, and caspase-3-dependent apoptosis, presenting potential as a novel therapy for advanced acute myeloid leukemia (AML).

Images & Validation

Key Properties

CAS Number2551033-16-8
MW399.44
FormulaC22H25NO6
SMILESO=C1NC=2C(OC3=CC=C(O)C=C3OC)=CC(OC)=CC2C(O)=C1CCCCC
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information