BIX02188 (c)

SKU: orb1226999

Description

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.

Key Properties

• CAS Number: 1094614-84-2
• MW: 412.48
• Purity: >98% (HPLC)
• Formula: C₂₅H₂₄N₄O₂
• SMILES: CN(C)CC1=CC(=CC=C1)N/C(=C\2/C3=C(C=C(C=C3)C(=O)N)NC2=O)/C4=CC=CC=C4
• Target: ERK
• Solubility: DMSO: 100 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ERK