Bitopertin (R enantiomer)

SKU: orb1710249

Description

Bitopertin R enantiomer (RG1678 R enantiomer) is the R-configuration isomer of Bitopertin, functioning as a potent and noncompetitive inhibitor of the glycine transporter 1 (GlyT1) with an IC50 of 25 nM. This compound is utilized in preclinical research to investigate GlyT1 function in neurological disorders, including schizophrenia, through in vitro binding assays and in vivo behavioral models.

Research Area

Neuroscience

Key Properties

• CAS Number: 845614-12-2
• MW: 543.46
• Formula: C₂₁H₂₀F₇N₃O₄S
• SMILES: C(=O)(C1=C(O[C@@H](C(F)(F)F)C)C=CC(S(C)(=O)=O)=C1)N2CCN(CC2)C3=C(F)C=C(C(F)(F)F)C=N3
• Target: GlyT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46837366