Bisindolylmaleimide III hydrochloride

SKU: orb3172932

Description

Bisindolylmaleimide III hydrochloride is a potent, highly selective protein kinase C (PKC) inhibitor. By competitively binding to the ATP pocket within the PKC catalytic domain, it completely blocks substrate phosphorylation cascades, widely used to investigate immune cell activation and tumor clonal proliferation mechanisms.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 683775-59-9
• MW: 420.89
• Purity: 99.62% (May vary between batches)
• Formula: C₂₃H₂₁ClN₄O₂
• SMILES: Cl.O=C1NC(=O)C(C2=CN(C=3C=CC=CC23)CCCN)=C1C4=CNC=5C=CC=CC54
• Target: PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PKC