BIRM 271

SKU: orb1819021

Description

BIRM 271 is a potent, enantiomerically pure inhibitor of arachidonic acid release, effectively suppressing the biosynthesis of leukotriene B4 (IC50 = 40 nM) and platelet-activating factor in human neutrophils. This small molecule is a valuable research tool for studying eicosanoid signaling in inflammation, applicable in both in vitro cellular assays and in vivo models of inflammatory diseases.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 149106-77-4
• MW: 335.44
• Purity: 99.78% (May vary between batches)
• Formula: C₂₁H₂₅N₃O
• SMILES: N([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4
• Target: LTR,Leukotriene Receptor,Phospholipase
• Solubility: DMSO:50 mg/mL (149.06 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BIRM271, BIRM-271, BIRM 271, LTB4, Phospholipase

Compound Identifiers

PubChem CID

9862559