bio-THZ1

SKU: orb1710252

Description

bio-THZ1 is a biotin-conjugated derivative of THZ1, a potent, selective, and irreversible covalent inhibitor of CDK7 (IC50 = 3.2 nM). This tool compound is widely used in proteomics and target engagement studies, facilitating research into transcription and cell cycle regulation in both cellular and animal models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1604811-14-4
• MW: 1053.67
• Formula: C₅₂H₆₅ClN₁₂O₈S
• SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCNC(=O)NCCCN(C)C\C=C\C(=O)Nc3ccc(cc3)C(=O)Nc3cccc(Nc4ncc(Cl)c(n4)-c4c[nH]c5ccccc45)c3)[C@@]1([H])NC(=O)N2
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139035075