BIO-2007817

SKU: orb2802464

Description

BIO-2007817 is a potent positive allosteric modulator (PAM) of the E3 ubiquitin ligase Parkin, exhibiting an EC50 of 0.17 µM. It enhances wild-type Parkin activity, promotes its autoubiquitination, and increases mono-ubiquitinated Miro1. This small molecule is a valuable research tool for studying Parkin function in Parkinson's disease models, both in vitro and in vivo.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• MW: 552.67
• Formula: C₃₂H₃₆N₆O₃
• Target: E1/E2/E3 Enzyme,PTEN,DNA/RNA Synthesis,Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E1/E2/E3 Enzyme,PTEN,DNA/RNA Synthesis,Antibacterial