BIO-013077-01

SKU: orb1299029

Description

BIO-013077-01 is a small molecule antagonist that potently inhibits TGFβ family type I receptors, including ALK4, ALK5, and ALK7. It is a valuable research tool for studying TGFβ signaling in cancer, fibrosis, and immunology, with demonstrated utility in both cellular assays and in vivo disease models.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 746667-48-1
• MW: 287.32
• Purity: 99.87% (May vary between batches)
• Formula: C₁₇H₁₃N₅
• SMILES: Cc1cccc(n1)-c1n[nH]cc1-c1ccc2nccnc2c1
• Target: TGF-beta/Smad
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.48 mM);DMSO:10 mg/mL (34.8 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, fibrosis, Inhibitor, BIO 013077 01, BIO01307701, BIO-013077-01, autophosphorylation, Alkylation, ALK5, Transforming growth factor beta receptors, TGFbeta/Smad, TGFbeta, TGF-beta, TGFβ, TGF-β/Smad, TGF-β Receptor, TGF-b/Smad, TGFb, Smad, pyrazoles

Compound Identifiers

PubChem CID

10469294