Bimolane

SKU: orb1221821

Description

Bimolane is a topoisomerase II inhibitor. Bimolane has been widely used in China as an anti-neoplastic agent and for the treatment of psoriasis. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. The results of enzyme and DNA titration assays indicate that inhibition of topoisomerase II by bimolane occurred through interactions with DNA, similar to the mechanism seen with the epipodophyllotoxin-type inhibitors. These results provide evidence that bimolane is an inhibitor of topoisomerase II in vitro.

Key Properties

• CAS Number: 74550-97-3
• MW: 452.51
• Purity: >98% (HPLC)
• Formula: C₂₀H₃₂N₆O₆
• SMILES: N1(C(=O)CN(CC1=O)CCN1CC(=O)N(C(=O)C1)CN1CCOCC1)CN1CCOCC1
• Target: Topo II

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AT-1727 | AT1727 | CCRIS 7574 | Bimolane

Quick Database Links

Gene Symbol

Topo II