Bifenthrin

SKU: orb2281187

Description

Bifenthrin is a synthetic pyrethroid insecticide used in research to study pesticide-induced cytotoxicity. It triggers apoptosis in bovine mammary epithelial cells via ROS generation, calcium dyshomeostasis, and MAPK pathway modulation, serving as a tool for in vitro mechanistic studies in toxicology and cell death research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 82657-04-3
• MW: 422.87
• Purity: 99.72% (May vary between batches)
• Formula: C₂₃H₂₂ClF₃O₂
• SMILES: C(=C(/C(F)(F)F)\Cl)\[C@H]1[C@@H](C(OCC2=C(C)C(=CC=C2)C3=CC=CC=C3)=O)C1(C)C
• Target: Sodium Channel,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.8 mM);DMSO:80 mg/mL (189.18 mM)

Bioactivity

• In Vitro:
  Bifenthrin. gambiae, and C. quinquefasciatus, with LD50 values ​​of 0.15 ng/mg and 0.16 ng/mg, respectively; contact of filter paper treated with bifenthrin with the tarsus of C. quinquefasciatus and A. gambiae at concentrations of 0.5% and 0.125%, respectively, resulted in 100% mortality .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, Bifenthrin

Compound Identifiers

PubChem CID

6442842