(+)-Bicuculline methiodide

SKU: orb1704660

Description

(+)-Bicuculline methiodide is a blood-brain barrier permeable GABAA receptor antagonist used to induce and study seizure activity in models of epilepsy. Its application extends to neuropharmacological research, where it is employed in both in vitro electrophysiology and in vivo studies investigating neurological disorders and septic pathophysiology.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 40709-69-1
• MW: 509.29
• Purity: 99.24%
• Formula: C₂₁H₂₀INO₆
• SMILES: C[N+]1(C)[C@]([C@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[I-]
• Target: GABA Receptor
• Solubility: DMSO:<25.46 mg/mL;H2O:<10.19 mg/ml

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bicuculline methiodide, ()Bicuculline methiodide, ( ) Bicuculline methiodide, d-Bicuculline methiodide, N-Methylbicuculline iodide, GABAReceptor, GABA Receptor, GABAA

Compound Identifiers

PubChem CID

104871