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Bicalutamide

SKU: orb1223699

Description

Bicalutamide is an oral non-steroidal anti-androgen for prostate Y. It binds to the androgen receptor.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number90357-06-5
MW430.37
Purity>98% (HPLC)
FormulaC18H14F4N2O4S
SMILESO=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)CS(=O)(C2=CC=C(F)C=C2)=O
TargetAndrogen Receptor (AR)
SolubilityEthanol: 5 mg/mL (11.61 mM); DMSO: 86 mg/mL (199.82 mM)

Bioactivity

In Vivo
Animal model: Castrate male mice, bearing LNCaP/AR(cs) xenograft tumors. Dosage: 10 mg/kg. Administration: Oral gavage, daily, for 28 days. Result: Inhibited tumors growth.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ICI 176334 | ZD 176334

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Protocol Information

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50 mg
$ 70.00
100 mg
$ 90.00
200 mg
$ 100.00
500 mg
$ 130.00
1 g
$ 150.00
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