BIBB 515

SKU: orb1690624

Description

BIBB 515 is a potent and selective inhibitor of 2,3-oxidosqualene cyclase (OSC), a key enzyme in sterol biosynthesis. It effectively reduces cholesterol levels in rodent models, as demonstrated in studies with normolipemic and hyperlipemic hamsters, making it a valuable research tool for investigating lipid metabolism and related disorders.

Research Area

Metabolism Research

Key Properties

• CAS Number: 156635-05-1
• MW: 380.87
• Purity: 99.68% (May vary between batches)
• Formula: C₂₂H₂₁ClN₂O₂
• SMILES: Clc1ccc(cc1)C(=O)N1CCC(CC1)=Cc1ccc(cc1)C1=NCCO1
• Target: LDLR,Others
• Solubility: Ethanol:0.15 mg/mL (0.39 mM);DMSO:2 mg/mL (5.25 mM)

Bioactivity

• Target IC50:
  OSC:3-oxidosqualene cyclase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cholesterol, cyclase, 2,3-oxidosqualene, BIBB 515, BIBB515, BIBB-515, LDL, effect, Inhibitor, lipid-lowering, inhibit, metabolism, OSC, sterol, Oxidosqualene cyclase

Compound Identifiers

PubChem CID

501398